WebJun 17, 2011 · The crystal structure of geranylgeranyl reductase (GGR) from Sulfolobus acidocaldarius was determined in order to elucidate the molecular mechanism of the … The Interpro database (EMBL-EBI) predicts over 8000 proteins present within the GGR family (InterPro code: IPR011777), with many homologous genes containing sequence identities as low as 20–30%. After sequence alignment, a phylogeny tree includes 1787 sequences of predicted GGR from the InterPro database. A … See more The 12 soluble proteins successfully isolated were tested for reductase activity on GGOH and FOH, and products obtained after enzymatic incubation were analyzed by GC–MS. … See more The 12 soluble GGRs successfully purified were tested for reductase activity on FPP and GGPP, and products were detected by LC–MS–TOF. Both farnesyl pyrophosphate (FPP, … See more Several synthetic approaches are currently being explored to perform selective hydrogenation on a few substrates [34,35,36]. Biological systems such as enoyl-CoA reductase … See more
Geranylgeranyl diphosphate reductase - Wikipedia
WebThis protein has been shown previously to stabilize geranylgeranyl reductase (GGR), a key enzyme in phytol biosynthesis. It is hypothesized that LIL3 functions to anchor GGR to membranes. First, we conjugated … WebBackground: Phytyl residues are the common side chains of chlorophyll (Chl) and tocopherols. Geranylgeranyl reductase (GGR), which is encoded by CHLP gene, is responsible for phytyl biosynthesis. The light-harvesting like protein LIL3 was suggested to be required for stability of GGR and protochlorophyllide oxidoreductase in Arabidopsis. convert 90 kilos to lbs
Identification of OsGGR2, a second geranylgeranyl …
WebDec 28, 2024 · Geranylgeranyl reductase (GGR) is a flavin-containing redox enzyme that hydrogenates a variety of unactivated polyprenyl substrates, which are further processed mostly for lipid biosynthesis in archaea or chlorophyll biosynthesis in plants. To date, only a few GGR genes have been confirmed to reduce polyprenyl substrates in vitro or in vivo. WebJul 14, 2015 · Decrease in α-tocopherol, and loss of the enzyme geranylgeranyl reductase (GGR, EC1.3.1.83) led to the conclusion that Lil3 stabilizes GGR against degradation . Recently, transmembrane … WebFeb 24, 2024 · Thus, it was demonstrated that the Z,E-mixed prenyl reductase family exists in the GGR homologs. To the best of our knowledge, this is the first identification of a new type of Z,E-mixed prenyl reductase with no sequence homology to PR-Dol. The substrate specificity of HepR significantly differed from that of GGR, suggesting that it is a new ... fallout before the war