WebJul 1, 2012 · Thus, both vegfr3/flt4 and ccbe1 are required for the formation of the entire lymphatic network in the zebrafish embryo. Interestingly, a ccbe1 mutant, full of fluid (fof hu3613), was reported to display oedema around the eye and the lower intestine (Hogan et al., 2009b), which supports our hypothesis that ccbe1 is required for both FL and IL ... WebFeb 9, 2024 · The collagen- and calcium-binding EGF-like domains 1 (CCBE1) is a secreted protein extensively described as indispensable for lymphangiogenesis during development enhancing VEGF-C signaling. In …

CCBE1 promotes tumor lymphangiogenesis and is negatively regulated …

WebNov 30, 2024 · Purpose: The identification and discovery of prognostic markers for colorectal cancer (CRC) are of great clinical significance. CCBE1 is expressed in various tumors and its expression correlates with lymphangiogenesis and angiogenesis. However, the association between CCBE1 expression and CRC outcome has not been reported. WebCCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like … hrw moh faq

The secreted lymphangiogenic factor CCBE1 is essential for ... - PubMed

WebApr 18, 2013 · Ccbe1 lacZ expression in prenatal and postnatal sites of erythropoiesis. (A,B) X-gal staining of E14.5 Ccbe1 lacZ and littermate control fetal liver is shown. (C,D) X-gal staining of bone marrow stroma from Ccbe1 lacZ and littermate control animals. Brain tissue from each animal was used as a control for the staining process (insets). WebCCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disulfide bonds. ... 蛋白别名: Collagen and calcium-binding EGF domain-containing protein 1; FLJ30681 ... WebNM_133459. 4 (CCBE1): c. 987+17_987+18del NM_133459. 4 (CCBE1): c. 988-154dup NM_133459. 4 (CCBE1): c. 988-179C>T NM_133459. 4 (CCBE1): c. 988-18T>C NM_133459. 4 (CCBE1): c. 988-19A>T NM_133459. 4 (CCBE1): c. 991C>T (p. Pro331Ser) Single allele The information on this website is not intended for direct diagnostic use or … hobbs community center