2024 B-naphthoflavone

B-naphthoflavone

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August undefined, 2024

Webβ-Naphthoflavone ≥99.0%. Supplier: TCI America. Synonyms: 3-Phenyl-1H-naphtho [2,1-b]pyran-1-one , 5,6-Benzoflavone. CAS Number: 6051-87-2. MDL Number: … WebSep 4, 2014 · Cardiac output (a), ventricular heart rate (b), stroke volume (c), and atrioventricular ratio (d) of zebrafish acutely exposed to β-naphthoflavone (BNF). Adult …

alpha-Naphthoflavone, 97%, Thermo Scientific Chemicals - Fisher Sci

WebSep 15, 2010 · General Function. Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Specific Function. Cytochromes P450 are a group of heme-thiolate monooxygenases. WebApr 14, 2024 · Objective: To investigate the dominant metabolic enzymes of six effective components (astragaloside IV, glycyrrhizic acid, calycosin-glucuronide, formononetin, ononin, calycosin-7-O-β-D- glucoside) of Huangqi Liuyi decoction extract (HQD).Methods: Mouse liver microsomes were prepared. The effects of specific inhibitors of CYP450 … list of large bi

b-Naphthoflavone = 98 6051-87-2

WebPooled B-naphthoflavone-treated Beagle dog liver microsomes male, 0.5 mL at 20 mg/mL (10 mg) 214: D1095: Pooled rifampin-treated Beagle dog liver microsomes male, 0.5 mL at 20 mg/mL (10 mg) 215: D1098: Pooled control, corn oil-treated Beagle dog liver microsomes male, 0.5 mL at 20 mg/mL (10 mg) 216: P2073 WebSep 1, 2006 · It has been reported that UGT1A1 is induced by 3-methylcholanthrene and b-naphthoflavone in HepG2 cells (Walle et al., 2000; Walle and Walle, 2002; Hanioka et al., 2006), and suggested that the ... WebBifunctional inducers include β-naphthoflavone, which induces both Phase I and Phase II drug-metabolizing enzymes by enhancing the AhR-XRE and Nrf2-ARE axes. Previous … imc texas heart

5,6-BENZOFLAVONE 6051-87-2 INDOFINE Chemical Company

Inducibility of UDP-glucuronosyltransferase 1As by β-naphthoflavone …

Webcompound, β-naphthoflavone (βNF) dissolved in corn oil at 0 or 50mg/kg-bw. Liver and gill samples were collected three days following injection. RNA Extraction: Total RNA was extracted from livers of 0 mg/kg-bw and 50 mg/kg-bw exposed sturgeon. RNA from 3 individuals from each treatment group were pooled before Upsequencing. WebAug 19, 2004 · Fluorination of the B ring obliterates aromatase inhibition by alpha-naphthoflavone derivatives (AJ2, AJ6, AJ8, and AJ9) or quinolin-4-one derivatives (A2 and A3). Effects of substitutions on the B ring of the synthetic flavones A7, A8, and A9 could not be discerned in our test system because flavone itself was not an inhibitor. imc thickness measurementWebThe first indication of species differences in AHR degradation was presented in studies that compared degradation of the endogenous AHR in the mouse Hepa-1 line (expressing the Ah b−1 AHR), mouse 3T3 fibroblasts (expressing the Ah b−2 AHR), mouse C2C12 myoblast cells (expressing the Ah b−2 AHR), and rat smooth muscle cells (A7). Analysis of total … list of large prime numbers

"Webβ-Naphthoflavone (BNF) is an exogenous ligand for aryl hydrocarbon receptor (AhR) in humans. It is an inducer of phase I detoxification enzymes (CYPs) and phase II … " - B-naphthoflavone

B-naphthoflavone

WebNaphthoflavone. Naphthoflavone may refer to: alpha -Naphthoflavone (7,8-benzoflavone) beta -Naphthoflavone (5,6-benzoflavone) This set index page lists … WebBoth fluvoxamine and alpha-naphthoflavone inhibited the metabolism of phenacetin significantly, and the inhibition constants (K(i)) were (5.4+/-1.0) micromol/L and (10.4+/-0.5) micromol/L, respectively. The activity of microsomes pretreated with diphenytriazol for 4 d was similar to that in b-naphthoflavone group, but was significantly ...

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Webβ-Naphthoflavone has been used: as aryl hydrocarbon receptor agonist to elucidate its effect on Cyp1A1 expression in embryos of transgenic cytochrome P450 1A1 (cyp1a) reporter zebrafish[]; as AhR agonists, to treat primary normal human epidermal keratinocytes (NHEKs) to study about aryl hydrocarbon receptor (AhR) activation by … Webα-Naphthoflavone Item No. 16924 CAS Registry No.: 604-59-1 Formal Name: 2-phenyl-4H-naphtho[1,2-b]pyran-4-one Synonyms: 7,8-Benzoflavone, NSC 407011 MF: C 19H 12O …

WebBackground α-Naphthoflavone (α-NF), also known as 7,8-benzoflavone and 2-phenyl-benzo (h)chromen-4-one, is a synthetic flavone derivative. α-Naphthoflavone is a potent … WebOct 13, 2024 · Abstract. β-Naphtoflavone (β-NF) is a flavonoid and enhances oxidative stress in vertebrates with little information from aquatic invertebrates as yet. In this study, we investigated the effects of β-NF on the antioxidant defense systems of the intertidal copepod Tigriopus japonicus. To measure the β-NF-triggered changes in oxidative …

WebSep 4, 2014 · Cardiac output (a), ventricular heart rate (b), stroke volume (c), and atrioventricular ratio (d) of zebrafish acutely exposed to β-naphthoflavone (BNF). Adult zebrafish were exposed for 48 h in a static medium to either BNF or solvent control immediately after which cardiac measurements were taken in clean water. WebB-naphthoflavone (BNF) induction of microsomal cytochrome P-488 and its effect on liver phospholipid metabolism were examined in rainbow trout (Salmo gairdneri) 24 and 96 hr …

WebThe effect of beta-naphthoflavone (beta-NF) on several catalytic activities of cytochrome P450 (CYP) and phase II enzymes putatively controlled by [Ah]-receptor activation …

WebJan 29, 2015 · 7,8 Benzoflavone is a synthetic flavone derivative, which is a potent aromatase inhibitor. It is known as alpha-naphthoflavone, and it shouldn't be confused with 5,6 benzo, known as, beta-naphthoflavone, which is an inducer of detoxification enzymes and is not an aromatase inhibitor at all. Fig 1. 7,8 Benzoflavone chemical structure. imct internalWebDec 20, 2024 · In the present study, we examined the therapeutic potential of beta-naphthoflavone (BNF), a synthetic derivative of a naturally occurring flavonoid, in … imc thrombosis clinicWebJun 26, 2011 · Prolonged hyperoxia contributes to bronchopulmonary dysplasia (BPD) in preterm infants. β- Naphthoflavone (BNF) is a potent inducer of cytochrome P450 (CYP)1A enzymes, which have been implicated ... imc toolingWebWe integrated cellular and molecular biological techniques to examine the effects of beta-naphthoflavone (BNF) exposure in lake trout brain CYP1A distribution and dynamics. … imctiWebDec 12, 2024 · Moreover, the rapid proliferation of IECs is a risk factor for radiation damage. β-naphthoflavone (BNF) is an agonist of the aryl hydrocarbon receptor (AhR) and … list of large flightless birdsβ-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and as such is an inducer of such detoxification enzymes as cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). β-Naphthoflavone is a putative chemopreventive agent. list of largest airlinesWebβ-Naphthoflavone Molecular Formula CHO Average mass 272.297 Da Monoisotopic mass 272.083740 Da ChemSpider ID 2271 More details: Names Properties Searches Spectra … imc tilburg