WebJun 17, 2002 · The alginate beads are coated with chitosan by ionic interaction during preparation. A retarded release of highly-soluble drugs like nitrofurantoin and timolol maleate or a prodrug was observed with the chitosan-treated beads Citation 34-36. An enteric protection of a preparation with the drug diclofenac was demonstrated by mixing the … WebDec 4, 2015 · In this work alginate and alginate-chitosan beads containing celecoxib solubilized into a self-emulsifying phase were developed in order to obtain a drug …
Frontiers In vitro Digestion and Swelling Kinetics of …
WebOct 12, 2006 · Calcium-alginate beads, chitosan-coated alginate beads and alginate-chitosan mixed beads were synthesized and their morphology was investigated by scanning electron microscopy. The swelling ability of the beads in different media was found to be dependent on the presence of the polyelectrolyte complex between alginate and … WebAug 1, 2013 · Fig. 2 a represents the FTIR spectra of pure chitosan and pure alginate and Fig. 2 b shows chitosan/alginate hydrogels with the compositions of (1/1) and (1/2), respectively. As seen from Fig. 2 a and b the characteristic absorption band at 1620 cm −1 assigned the peak of the carbonyl (C O) bond in the spectrum of alginate shifted to a … siamsa horse
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WebDec 4, 2015 · In this work alginate and alginate-chitosan beads containing celecoxib solubilized into a self-emulsifying phase were developed in order to obtain a drug delivery system for oral administration, able to delay the drug release in acidic environment and to promote it in the intestinal compartment. The rationale of this work was linked to the … WebApr 14, 2024 · A similar result was also observed by Gaserod, Smidsrod, and Skjak-Braek (1998) for alginate beads coated with chitosan. When the chitosan solution pH rose from 4.00 to 6.00, an increase in the rate of binding of … WebDec 18, 2015 · The aim of this study was to fabricate composite gel beads based on natural polysaccharides. Hyaluronic acid (HA) and Chitosan (CS) were successfully admixed with Ca2+/alginate (SA) gel system to produce SA/HA/CS gel beads by dual crosslinking: the ionic gelation and the polyelectrolyte complexation. The preparation procedure was that … the peninsulas mount pleasant tx